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Journal of Antimicrobial Chemotherapy (2002) 49, 169-172
© 2002 The British Society for Antimicrobial Chemotherapy


Brief report

Plasmid-mediated TEM-3 extended-spectrum ß-lactamase production in Salmonella typhimurium in Casablanca

Rajaa AitMhanda, Abdelaziz Soukrib, Najat Moustaouia, Hamid Amarouchb, Naima ElMdaghria, Danielle Sirotc and Mohamed Benbachira,*

a IbnRochd University Hospital and b Faculté des Sciences I AinChock, Casablanca, Morocco; c Faculté de Médecine Clermont-Ferrand, France

Isolates of extended-spectrum ß-lactamase (ESBL)-producing Salmonella typhimurium were recovered from children admitted to the IbnRochd University Hospital of Casablanca in 1994. These isolates produced TEM-3 as shown by PCR, isoelectric focusing and sequencing. Production of TEM-3 and resistance to gentamicin were encoded by a 10 kb plasmid that could be transferred by conjugation and transformation. This report extends the list of ESBLs produced by S. typhimurium and stresses the need for continuous surveillance of non-typhoidal Salmonella to adapt antibiotic treatment and preventive measures.

* Correspondence address. Faculté de Médecine, Laboratoire de Microbiologie, BP 9154 Casablanca, Morocco. Tel/Fax: +212-22269057; E-mail: benbachir{at}casanet.net.ma


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