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Journal of Antimicrobial Chemotherapy (2001) 47, 685-688
© 2001 The British Society for Antimicrobial Chemotherapy

Brief report

SHV-type extended-spectrum ß-lactamase in a Shigella flexneri clinical isolate

Nicolas Fortineaua,*, Thierry Naasa, Olivier Gaillotb and Patrice Nordmanna

a Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre; b Service de Bactériologie-Virologie, Centre Hospitalier et Universitaire de Rennes 35033 Rennes, France

A Shigella flexneri isolate resistant to oxyimino-cephalosporins was recovered from a stool sample of a 16 month-old Algerian child hospitalized in Paris, France. This isolate harboured an SHV-2 ß-lactamase gene located on a c. 80 kb self-transferable plasmid. This is the first report of an Ambler class A extended-spectrum ß-lactamase from Shigella spp.

* Corresponding author. Tel: +33-1-45-21-20-19; Fax: +33-1-45-21-63-40; E-mail: nicolas.fortineau{at}bct.ap-hop-paris.fr


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