Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (1)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Thrane, N.
Right arrow Articles by Schønheyder, H. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Thrane, N.
Right arrow Articles by Schønheyder, H. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (2001) 47, 211-214
© 2001 The British Society for Antimicrobial Chemotherapy

Brief report

Individual use of antibiotics and prevalence of ß-lactamase production among bacterial pathogens from middle ear fluid

Nana Thranea,b,*, Charlotte Olesena, Henrik T. Sørensenc,d and Henrik C. Schønheyderc,e

a The Danish Epidemiology Science Centre, Department of Epidemiology and Social Medicine, University of Aarhus, Aarhus C; b The Medical Research Unit, Ringkjøbing County; c The Clinical Epidemiological Research Unit, Aalborg Hospital, Aalborg; d The Department of Medicine V, Aarhus University Hospital, Aarhus C; e The Department of Clinical Microbiology, Aalborg Hospital, Aalborg, Denmark

Prescription data and clinical laboratory data were analysed to assess the influence of previous antibiotic therapy on the prevalence of ß-lactamase in isolates of Haemophilus influenzae and Moraxella catarrhalis from primary specimens of middle ear fluid from 2129 children aged 0–5 years. The prevalence of ß-lactamase-positive H. influenzae was 6.6% [95% confidence interval (CI): 3.5–9.8%] in children who received antibiotics 5–90 days before isolation of the organism compared with 7.0% (95% CI: 3.9–10.2%) in those who did not. The prevalence of ß-lactamase-positive M. catarrhalis was 90.9% (95% CI: 84.0–97.8%) in children who received antibiotics compared with 86.7% (95% CI: 79.0–94.4%) in those who did not.

* Correspondence address. The Danish Epidemiology Science Centre, University of Aarhus, Vennelyst Boulevard 6, 8000 Aarhus C, Denmark. Tel: +45-8942-6111; Fax: +45-8613-1580; E-mail: nthrane{at}dadlnet.dk


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.