Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (30)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Wainwright, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wainwright, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (2001) 47, 1-13
© 2001 The British Society for Antimicrobial Chemotherapy

Review

Acridine—a neglected antibacterial chromophore

Mark Wainwright*

Centre for Forensic Science, University of Central Lancashire, Preston PR1 2HE, UK

The use of acridines as antimicrobial agents was first proposed by Ehrlich and Benda in 1912, and the first clinical use of these agents occurred in 1917. Many compounds containing the acridine chromophore were synthesized and tested, and the aminoacridines found wide use, both as antibacterial agents and as antimalarials, during World War II. The emergence of the penicillins eclipsed the acridines in antisepsis due to the greater therapeutic efficacies of the former. However, with the current massive increases in drug-resistant bacterial infection, new acridine derivatives may be of use. In addition, the topical utilization of aminoacridines in conjunction with directed low-power light offers bactericidal action at much lower doses.

* E-mail: MWainwright{at}UCLan.ac.uk


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Virol.Home page
K.-J. Jung, A. Dasgupta, K. Huang, S.-J. Jeong, C. Pise-Masison, K. V. Gurova, and J. N. Brady
Small-Molecule Inhibitor Which Reactivates p53 in Human T-Cell Leukemia Virus Type 1-Transformed Cells
J. Virol., September 1, 2008; 82(17): 8537 - 8547.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
M. L. Quinlivan, K. Ayres, H. Ran, S. McElwaine, M. Leedham-Green, F. T. Scott, R. W. Johnson, and J. Breuer
Effect of Viral Load on the Outcome of Herpes Zoster
J. Clin. Microbiol., December 1, 2007; 45(12): 3909 - 3914.
[Abstract] [Full Text] [PDF]

Home page
 J. Dent. Res.Home page
J.B. Epstein, S. Elad, E. Eliav, R. Jurevic, and R. Benoliel
Orofacial Pain in Cancer: Part II--Clinical Perspectives and Management
J. Dent. Res., June 1, 2007; 86(6): 506 - 518.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.