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Journal of Antimicrobial Chemotherapy (2000) 45, 695-699
© 2000 The British Society for Antimicrobial Chemotherapy

Brief reports

Surveillance of antimicrobial resistance among Gram-negative isolates from intensive care units in eight hospitals in Turkey

Study group: Sebahat Aksaraya,*, Basak DokuzoGuza, Engin Güvenera, Mine Yücesoyb, Nuran YuluGb, Sesin Kocagözc, Serhat Ünalc, Sila Çetind, Semra Çalangud,*, Murat Günaydine, Hakan LeblebicioGlue, Saban Esene, Banu Bayarf, Ayse Willkef, Duygu Findikg, Inci Tuncerg, Bülent Baysalg, Filiz Günserenh and Latife MamikoGluh

a Ankara Numune Hospital; b Dokuz Eylül University Faculty of Medicine; c Hacettepe University Faculty of Medicine; d Ankara Numune Hospital; e Ondokuz Mayis University Faculty of Medicine; f A. Ü. Ibn-i Sina Hospital; g Selçuk University Faculty of Medicine; h Akdeniz University Faculty of Medicine, Turkey

With the participation of eight major reference hospitals in Turkey, 749 aerobic Gram-negative isolates obtained from 473 intensive care patients in 1997 were tested for their susceptibility to 13 commonly employed antibacterial agents. The frequency with which species were isolated and resistance rates were compared with data from the previous 2 years. Imipenem was the most active agent against the majority of isolates (75%), followed by ciprofloxacin, cefepime and amikacin. The per cent susceptibility to all antibiotics declined from 1995 to 1996. With the exception of imipenem, for which there was no change in resistance, the per cent susceptibility somewhat increased in 1997. However, it was still lower than in 1995.

* Corresponding author.


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