Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (25)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Zhanel, G. G.
Right arrow Articles by Hoban, D. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhanel, G. G.
Right arrow Articles by Hoban, D. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (2000) 45, 655-662
© 2000 The British Society for Antimicrobial Chemotherapy

Antibiotic resistance in respiratory tract isolates of Haemophilus influenzae and Moraxella catarrhalis collected from across Canada in 1997–1998

George G. Zhanela,b,c,d, James A. Karlowskya,b,d,*, Donald E. Lowe, The Canadian Respiratory Infection Study Group and Daryl J. Hobana,d

Department of Medical Microbiology, a Faculty of Medicine and b Faculty of Pharmacy, University of Manitoba and c Departments of Medicine and d Clinical Microbiology, Health Sciences Centre, Winnipeg, Man. R3A 1R9; e Department of Microbiology, Mt Sinai Hospital, Toronto, Ont. M5G 1XS, Canada

Between September 1997 and November 1998 respiratory tract isolates of Haemophilus influenzae (n = 1352) and Moraxella catarrhalis (n = 428) were collected by 18 Canadian medical centres. ß-Lactamase was produced by 24.0 and 94.2% of H. influenzae and M. catarrhalis isolates, respectively. Resistance rates for H. influenzae were highest for ampicillin (24.0%), trimethoprim/sulphamethoxazole (13.7%), loracarbef (6.1%) and cefaclor (4.2%), and <= 1% for amoxycillin/clavulanate, cefotaxime, cefprozil, cefixime, imipenem, ciprofloxacin, levofloxacin, grepafloxacin, trovafloxacin and chloramphenicol. M. catarrhalis resistance rates, derived using NCCLS breakpoint criteria for Haemophilus spp., were <= 1% for all antibiotics tested except ampicillin (49.5%) and trimethoprim/sulphamethoxazole (1.6%).

* Correspondence address. Department of Clinical Microbiology, Health Sciences Centre, MS673, 820 Sherbrook Street, Winnipeg, Man. R3A 1R9, Canada. Tel: +1-204-787-4683; Fax: +1-204-787-4699; E-mail: jkarlowsky{at}hsc.mb.ca


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Appl. Environ. Microbiol.Home page
A. Saeed-Kothe, W. Yang, and S. D. Mills
Use of the Riboflavin Synthase Gene (ribC) as a Model for Development of an Essential Gene Disruption and Complementation System for Haemophilus influenzae
Appl. Envir. Microbiol., July 1, 2004; 70(7): 4136 - 4143.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.