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Journal of Antimicrobial Chemotherapy (1999) 43, 145-148
© 1999 The British Society for Antimicrobial Chemotherapy


Brief reports

Increasing fluoroquinolone resistance in salmonella serotypes in Finland during 1995–1997

Antti Hakanena,c,*, Anja Siitonenb, Pirkko Kotilainenc and Pentti Huovinena

a Antimicrobial Research Laboratory, National Public Health Institute, Turku; b National Salmonella Reference Centre, Laboratory of Enteric Pathogens, National Public Health Institute, Helsinki; c Department of Medicine, Turku University, Turku, Finland

Abstract

Antimicrobial resistance trends were examined for 811 salmonella isolates from humans collected in Finland during 1995–1997. The material was divided into domestic and foreign isolates according to the origin of infection. A total of 2.3% of the 387 domestic and 7.8% of the 424 foreign isolates were quinolone-resistant (P < 0.001). Among the domestic isolates we detected an emergence of ciprofloxacin resistance (MIC >= 0.25 mg/L) with the proportion of resistant isolates increasing from 0 to 2.2% (P = 0.2). Among the foreign isolates this increase was even more dramatic, from 2.0% to 8.4% (P = 0.037) during the study period.

Notes

* Correspondence address. Antimicrobial Research Laboratory, National Public Health Institute, PO Box 57, 20521 Turku, Finland. Tel +358-2-2519255; Fax: +358-2-2519254 E-mail: antti.hakanen{at}utu.fi


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