Journal of Antimicrobial Chemotherapy, Vol 41, 25-29, Copyright © 1998 by The British Society for Antimicrobial Chemotherapy
GE Griffin
Studies of the cytokine cascade in animal models of infection and human
experiments involving endotoxin infusion have contributed fundamentally to
understanding the role of cytokines in human sepsis. The complexity of this
cytokine cascade has been difficult to unravel in clinical sepsis. However,
the Jarisch-Herxheimer reaction has been identified as a model of the
cytokine cascade in human sepsis and has provided an excellent model for
experiments involving blocking agents. TNF blocking has been shown to be
important for protection in animal models of sepsis, but has been somewhat
disappointing in humans because adverse events have generally outweighed
benefits.
ORIGINAL ARTICLES
Cytokines involved in human septic shock--the model of the Jarisch- Herxheimer reaction
Division of Infectious Diseases, St George's Hospital Medical School, Tooting, London, UK.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Ates, A. Algul, O. Gecici, U. Semiz, O. Yilmaz, and M. Gulsun Olanzapine treatment in Jarisch-Herxheimer reaction due to neurosyphilis with dementia: a case report J Psychopharmacol, November 1, 2009; 23(8): 999 - 1000. [Abstract] [PDF]
|
|
|
|
 |
|
 D. Bibbal, V. Dupouy, M. F. Prere, P. L. Toutain, and A. Bousquet-Melou Relatedness of Escherichia coli Strains with Different Susceptibility Phenotypes Isolated from Swine Feces during Ampicillin Treatment Appl. Envir. Microbiol., May 15, 2009; 75(10): 2999 - 3006. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. M. Nam, S. K. Lim, H. M. Kang, J. M. Kim, J. S. Moon, K. C. Jang, J. M. Kim, Y. S. Joo, and S. C. Jung Prevalence and antimicrobial susceptibility of gram-negative bacteria isolated from bovine mastitis between 2003 and 2008 in Korea J Dairy Sci, May 1, 2009; 92(5): 2020 - 2026. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.-H. Zhao, Z.-Q. Hu, and T. Shimamura Potency of IMP-10 metallo-{beta}-lactamase in hydrolysing various antipseudomonal {beta}-lactams J. Med. Microbiol., August 1, 2008; 57(8): 974 - 979. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Silverstein and D. C. Johnson Endogenous versus exogenous glucocorticoid responses to experimental bacterial sepsis J. Leukoc. Biol., April 1, 2003; 73(4): 417 - 427. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Spanu, F. Luzzaro, M. Perilli, G. Amicosante, A. Toniolo, and G. Fadda Occurrence of Extended-Spectrum {beta}-Lactamases in Members of the Family Enterobacteriaceae in Italy: Implications for Resistance to {beta}-Lactams and Other Antimicrobial Drugs Antimicrob. Agents Chemother., January 1, 2002; 46(1): 196 - 202. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. S. Thomson and E. S. Moland Cefepime, Piperacillin-Tazobactam, and the Inoculum Effect in Tests with Extended-Spectrum beta -Lactamase-Producing Enterobacteriaceae Antimicrob. Agents Chemother., December 1, 2001; 45(12): 3548 - 3554. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Heritage, N. Ransome, P. A. Chambers, and M. H. Wilcox A comparison of culture and PCR to determine the prevalence of ampicillin-resistant bacteria in the faecal flora of general practice patients J. Antimicrob. Chemother., August 1, 2001; 48(2): 287 - 289. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Stock and B. Wiedemann Natural Antibiotic Susceptibilities of Edwardsiella tarda, E. ictaluri, and E. hoshinae Antimicrob. Agents Chemother., August 1, 2001; 45(8): 2245 - 2255. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Marchandin, H. Jean-Pierre, C. De Champs, D. Sirot, H. Darbas, P. F. Perigault, and C. Carriere Production of a TEM-24 Plasmid-Mediated Extended-Spectrum beta -Lactamase by a Clinical Isolate of Pseudomonas aeruginosa Antimicrob. Agents Chemother., January 1, 2000; 44(1): 213 - 216. [Abstract] [Full Text]
|
|
|
|
|
|
G. S. Babini and D. M. Livermore Effect of conalbumin on the activity of Syn 2190, a 1,5 dihydroxy-4-pyridon monobactam inhibitor of AmpC {beta}-lactamases J. Antimicrob. Chemother., January 1, 2000; 45(1): 105 - 109. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 U. Winkler, M. Jensen, O. Manzke, H. Schulz, V. Diehl, and A. Engert Cytokine-Release Syndrome in Patients With B-Cell Chronic Lymphocytic Leukemia and High Lymphocyte Counts After Treatment With an Anti-CD20 Monoclonal Antibody (Rituximab, IDEC-C2B8) Blood, October 1, 1999; 94(7): 2217 - 2224. [Abstract] [Full Text] [PDF]
|
|