Journal of Antimicrobial Chemotherapy, Vol 41, 307-310, Copyright © 1998 by The British Society for Antimicrobial Chemotherapy
G Bonfiglio, V Carciotto, G Russo, S Stefani, GC Schito, E Debbia and G Nicoletti
In order to assess the current level of resistance to widely used
antipseudomonal antibiotics in clinical isolates of Pseudomonas aeruginosa,
a national survey was undertaken. Fifteen hospitals throughout Italy
participated in the study. The University of Catania tested the antibiotic
susceptibility of 1005 consecutive clinically significant P. aeruginosa
collected from March to June 1995. Lack of susceptibility, according to
NCCLS breakpoints, was at the following rates: meropenem, 9.1%; imipenem,
19.3%; ceftazidime, 13.4%; carbenicillin, 27.3%; piperacillin, 12%;
ticarcillin/clavulanic acid, 22.8%; amikacin, 10.6%; and ciprofloxacin,
31.9%. About half of the isolates (44.4%) were not susceptible to at least
one of the antibiotics tested.
ORIGINAL ARTICLES
Antibiotic resistance in Pseudomonas aeruginosa: an Italian survey
Istituto di Microbiologia, Universita di Catania, Italy.
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