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Journal of Antimicrobial Chemotherapy (1978) 4, 273-278
© 1978 The British Society for Antimicrobial Chemotherapy

research-article

Kanamycin resistance in Povidencia stuartii

P. McHale, L. English, A. Speekenbrink, C. Keane* and R. Wise

Clinical Microbiology Unit, Dublin University, Adelaide Hospital Peter Street, Dublin 8, Eire Microbiology Department, Dudley Road Hospital Dudley Road, Birmingham B18 7QH, England

accepted 31 October 1977

*To whom all correspondence and reprint requests should be addressed.

An increase in the frequency of isolation over a five year period from hospital specimens, of KmR (MIC> 100 mg/1) P. stuartii of various serotypes is reported. Resistance to Km, Nm, Cb and Ap (16 strains); Km, Nm, Su (one strain); and Km, Nm, Cb, Ap, Su (one strain) could be transferred to E. coli J5-3 rif. Inactivation of Km and Nm was by phosphorylation. Two types of phosphorylase, distinguishable by their action on Nm, were noted.


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