Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (10)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Hamilton-Miller, J. M.
Right arrow Articles by Shah, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hamilton-Miller, J. M.
Right arrow Articles by Shah, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy, Vol 39, 575-584, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy

JOURNAL ARTICLE

In-vitro microbiological assessment of a new penem, Men 10700

JM Hamilton-Miller and S Shah
Department of Medical Microbiology, Royal Free Hospital School of Medicine, London, UK.

The in-vitro antibacterial activity of Men 10700, a novel penem, has been compared with that of ritipenem, ciprofloxacin, amikacin, cefotaxime and co-amoxiclav against 539 strains taken from 17 genera. Men 10700 was most active against staphylococci and streptococci (MIC90 < 0.5 mg/L), slightly less active against Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Citrobacter spp., Moraxella catarrhalis and peptostreptococci (MIC90 0.5-2 mg/L), moderately active against Enterococcus faecalis, members of the tribe Proteae, Serratia marcescens, Acinetobacter spp., clostridia and Bacteroides spp. (MIC90 4-16 mg/L), and inactive against Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Enterococcus faecium. Its antibacterial spectrum is thus slightly less broad than that of imipenem, but it compares favourably with an oral third-generation cephalosporin. Men 10700 was more active than ritipenem against many species, especially Enterobacter spp. and Citrobacter spp.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Antimicrob ChemotherHome page
G. A. Pankuch, D. B. Hoellman, M. R. Jacobs, and P. C. Appelbaum
Antipneumococcal activity of MEN 10700, a new penem, compared with other compounds, by MIC and time–kill kinetics
J. Antimicrob. Chemother., September 1, 1999; 44(3): 381 - 384.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
J. M. T. Hamilton-Miller and S. Shah
Effect of antibiotic concentration on the killing of Staphylococcus aureus and Enterococcus faecalis: comparison of the novel penem, Men 10700, with other {beta}-lactam antibiotics
J. Antimicrob. Chemother., September 1, 1999; 44(3): 418 - 420.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.