Journal of Antimicrobial Chemotherapy, Vol 39, 135-140, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy
J Renneberg, LL Niemann and E Gutschik
A total of 278 streptococci isolated from blood (including 66 strains of
Streptococcus pneumoniae) were tested for their MIC to penicillin G,
gentamicin, rifampicin, clindamycin, erythromycin, vancomycin and
teicoplanin to determine the current state of resistance among streptococci
isolated from blood at a University Hospital in Copenhagen, Denmark, and
thereby to assess alternative treatment for patients who are infected with
a penicillin-resistant streptococcal strain or allergic to penicillin.
Danish Blood Sensitivity Agar and the Etest were used. Overall, resistance
to penicillin among Streptococcus mitis strains was 44.4% (37%
intermediately susceptible and 7.4% resistant). As penicillin resistance in
S. mitis may be an early indication of emerging penicillin resistance among
other streptococcal species, this finding is a matter of concern. Except
for this observation, penicillin remains the best and a safe choice for
treatment of streptococcal infection. For alternative treatment when the
patient is allergic to penicillin and for prophylaxis, the usual
recommendation is macrolide antibiotics or clindamycin. The majority of
non-enterococcal groups of streptococci remain sensitive to erthromycin and
clindamycin, but the antibiotic susceptibility pattern is unpredictable
without testing the isolates, so empirical therapy or prophylaxis may fail.
JOURNAL ARTICLE
Antimicrobial susceptibility of 278 streptococcal blood isolates to seven antimicrobial agents
Department of Clinical Microbiology, University of Copenhagen, Denmark.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  D. F. J. Brown, R. Hope, D. M. Livermore, G. Brick, K. Broughton, R. C. George, R. Reynolds, and on behalf of the BSAC Working Parties on Resistanc Non-susceptibility trends among enterococci and non-pneumococcal streptococci from bacteraemias in the UK and Ireland, 2001-06 J. Antimicrob. Chemother., November 1, 2008; 62(suppl_2): ii75 - ii85. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. C. Y. Chow, P. M. Hawkey, E. W. C. Chan, M. L. Chin, T. K. Au, D. K. C. Fung, and R. C. Y. Chan High-Level Gentamicin Resistance Mediated by a Tn4001-Like Transposon in Seven Nonclonal Hospital Isolates of Streptococcus pasteurianus Antimicrob. Agents Chemother., July 1, 2007; 51(7): 2508 - 2513. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Rodriguez-Avial, C. Rodriguez-Avial, E. Culebras, and J. J. Picazo In Vitro Activity of Telithromycin against Viridans Group Streptococci and Streptococcus bovis Isolated from Blood: Antimicrobial Susceptibility Patterns in Different Groups of Species Antimicrob. Agents Chemother., February 1, 2005; 49(2): 820 - 823. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.-C. Chiang, J.-C. Tsai, S.-Y. Chen, C.-Y. Hsu, C.-T. Wu, L.-J. Teng, and P.-R. Hsueh Mycotic Aneurysm Caused by Streptococcus constellatus subsp. constellatus J. Clin. Microbiol., April 1, 2004; 42(4): 1826 - 1828. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Task Force Members, D. Horstkotte, F. Follath, E. Gutschik, M. Lengyel, A. Oto, A. Pavie, J. Soler-Soler, G. Thiene, A. von Graevenitz, et al. Guidelines on Prevention, Diagnosis and Treatment of Infective Endocarditis Executive Summary: The Task Force on Infective Endocarditis of the European Society of Cardiology Eur. Heart J., February 1, 2004; 25(3): 267 - 276. [Full Text] [PDF]
|
|
|
|
|
|
A. J. Smith and M. S. Jackson Susceptibility of viridans group streptococci isolated from dento-alveolar infections to eight antimicrobial agents J. Antimicrob. Chemother., December 1, 2003; 52(6): 1045 - 1046. [Full Text] [PDF]
|
|
|
|
|
|
H. Seppala, M. Haanpera, M. Al-Juhaish, H. Jarvinen, J. Jalava, and P. Huovinen Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from normal flora J. Antimicrob. Chemother., October 1, 2003; 52(4): 636 - 644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L.-J. Teng, P.-R. Hsueh, S.-W. Ho, and K.-T. Luh High Prevalence of Inducible Erythromycin Resistance among Streptococcus bovis Isolates in Taiwan Antimicrob. Agents Chemother., December 1, 2001; 45(12): 3362 - 3365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Dancer The problem with cephalosporins J. Antimicrob. Chemother., October 1, 2001; 48(4): 463 - 478. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Perez-Trallero, D. Vicente, M. Montes, J. M. Marimon, and L. Pineiro High proportion of pharyngeal carriers of commensal streptococci resistant to erythromycin in Spanish adults J. Antimicrob. Chemother., August 1, 2001; 48(2): 225 - 229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Rodriguez-Avial, C. Rodriguez-Avial, E. Culebras, A. Benitez, and J. J. Picazo Distribution of mef(A) and erm(B) genes in macrolide-resistant blood isolates of viridans group streptococci J. Antimicrob. Chemother., May 1, 2001; 47(5): 727 - 728. [Full Text] [PDF]
|
|
|
|
|
|
M. J. Mohammed and F. C. Tenover Evaluation of the PASCO Strep Plus Broth Microdilution Antimicrobial Susceptibility Panels for Testing Streptococcus pneumoniae and Other Streptococcal Species J. Clin. Microbiol., May 1, 2000; 38(5): 1713 - 1716. [Abstract] [Full Text]
|
|
|
|
|
|
S. J. Rosser, M. J. Alfa, S. Hoban, J. Kennedy, and G. K. Harding E Test versus Agar Dilution for Antimicrobial Susceptibility Testing of Viridans Group Streptococci J. Clin. Microbiol., January 1, 1999; 37(1): 26 - 30. [Abstract] [Full Text]
|
|