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Journal of Antimicrobial Chemotherapy, Vol 39, 85-87, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy


JOURNAL ARTICLE

Novel transferable beta-lactam resistance with cephalosporinase characteristics in Salmonella enteritidis

O Gaillot, C Clement, M Simonet and A Philippon
Department of Microbiology, King Fahd Military Medical Complex, Dhahran, Kingdom of Saudi Arabia.

An isolate of Salmonella enteritidis was found to produce a plasmid- encoded beta-lactamase (DHA-1) that conferred resistance to extended- spectrum cephalosporins and cephamycins. The substrate and inhibition profiles of this enzyme resemble a class C beta-lactamase. This is the first report of a plasmid-mediated cephalosporinase of this class in the Salmonella genus.
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