Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (17)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Smith, M. D.
Right arrow Articles by White, N. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Smith, M. D.
Right arrow Articles by White, N. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (1996) 37, 611-615
© 1996 The British Society for Antimicrobial Chemotherapy

brief-report

n-vitro activity of carbapenem antibiotics against ß-lactam susceptible and resistant strains of Burkholderia pseudomallei

M. D. Smitha,b, V. Wuthiekanuna, A. L. Walsha,b and N. J. Whitea,b,*

aFaculty of Tropical Medicine, Mahidol University 420/6 Rajvithi Road, Bangkok 10400, Thailand bCentre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University Oxford, UK

Received 13 February 1995; returned 31 August 1995; accepted 15 October 1995

*Correspondence to: Dr N. J. White, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand

Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Clin. Microbiol. Rev.Home page
A. C. Cheng and B. J. Currie
Melioidosis: Epidemiology, Pathophysiology, and Management
Clin. Microbiol. Rev., April 1, 2005; 18(2): 383 - 416.
[Abstract] [Full Text] [PDF]

Home page
 Antimicrob. Agents Chemother.Home page
T. J. J. Inglis, F. Rodrigues, P. Rigby, R. Norton, and B. J. Currie
Comparison of the Susceptibilities of Burkholderia pseudomallei to Meropenem and Ceftazidime by Conventional and Intracellular Methods
Antimicrob. Agents Chemother., August 1, 2004; 48(8): 2999 - 3005.
[Abstract] [Full Text] [PDF]

Home page
 Antimicrob. Agents Chemother.Home page
A. C. Cheng, D. A. Fisher, N. M. Anstey, D. P. Stephens, S. P. Jacups, and B. J. Currie
Outcomes of Patients with Melioidosis Treated with Meropenem
Antimicrob. Agents Chemother., May 1, 2004; 48(5): 1763 - 1765.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
B.J. Currie
Melioidosis: an important cause of pneumonia in residents of and travellers returned from endemic regions
Eur. Respir. J., September 1, 2003; 22(3): 542 - 550.
[Abstract] [Full Text] [PDF]

Home page
 J Med MicrobiolHome page
N.J. BEECHING, C.A. HART, and B.I. DUERDEN
Tropical and exotic infections: Proceedings of the fifth Liverpool Tropical School Bayer Symposium on Microbial Diseases held on 14 February 1998
J. Med. Microbiol., January 1, 2000; 49(1): 5 - 27.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.