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Journal of Antimicrobial Chemotherapy (1995) 36, 815-819
© 1995 The British Society for Antimicrobial Chemotherapy

brief-report

Tetracycline resistance determinants, Tet B and Tet M, detected in Pasteurella haemolytica and Pasteurella multocida from bovine herds

Elisabeth Chaslus-Danclaa,*, Marie-Claude Lesage-Descausesa, Sabine Leroy-Sétrina, Jean-Louis Martelb and Jean-Pierre Lafonta

aInstitut National de la Recherche Agronomique (INRA), Centre de Tours-Nouzilly 37380, Monnaie, France bCentre National d Etudes Vétéerinaires et Alimentaires (CNEVA) BP 70330, Lyon, France

*Tel: + 33–47.42.77.65; Fax: + 33–47.42.77.74; Email:clisabeth.dancla{at}tours.inra.fr

Resistance to antibiotics has recently emerged in Pasteurella haemolytica and Pasteurella multocida isolated from bovine herds. Forty-two clinical strains resistant to antibiotics and isolated through a French national network from different origins were analysed for their resistance to tetracycline. The MICs of tetracycline ranged from 32–256 mg/L. The resistance determinants Tet B and Tet M were detected in two strains, in which they are probably chromosomal.


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