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Journal of Antimicrobial Chemotherapy (1988) 22, 759-763
© 1988 The British Society for Antimicrobial Chemotherapy

research-article

Response rates to a staged antibiotic regimen in febrile neutropenic patients

R. A. Barnes and T. R. Rogers

Department of Medical Microbiology, Charing Cross and Westminster Medical School 17 Horseferry Road, London SW1P 2AR, UK

Received 24 June 1987; returned 21 July 1988; accepted 21 July 1988

In a prospective study of 50 patients with prolonged neutropenia, we observed a 75% response rate to a staged empirical antibiotic regimen used to treat 101 episodes of fever. Additions or modifications to the protocol were rarely necessary. The use of an approach such as this improves the management of febrile neutropenic patients.


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