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Journal of Antimicrobial Chemotherapy (1987) 20, 373-378
© 1987 The British Society for Antimicrobial Chemotherapy

research-article

Fleroxacin (Ro 23-6240): activity in virtro against 355 enteropathogenic and non-fermentative Gram-negative bacilli and Legionella pneumophila

P. Hohia,*, A. von Graevenitzb and J. Zollinger-Itenb

aF.Hoffmann-La Roche, Pharmaceutical Research 4002 Basel bDepartment of Medical Microbiology, University of Zürich 8028 Zürich, Switzerland

Received 10 March 1987;

*Corresponding author

The antibacterial activity of fleroxacin (Ro 23-6240, AM-833), a new 6-fluoroquinolone, was determined against 149 strains of enteropathogenic bacteria (17 species) and 191 strains (28 species) of glucose non-fermentative Gram-negative rods (excluding Pseudomonas aeruginosa), and against 15 strains of Legionella pneumophila. The cumulative susceptibility of these groups of bacteria to Ro 23-6240 at the 2 mg/l level were 99.2% 80.1 and 100% of tested strains, respectively.


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