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Journal of Antimicrobial Chemotherapy (1987) 20, 357-362
© 1987 The British Society for Antimicrobial Chemotherapy


research-article

A comparison of the in-vitro activity of seventeen antibiotics against Streptococcus faecalis

J. L. Pérez, L. Riera, F. Valls, C. I. Berrocal and L. Berrocal

Laboratory of Microbiology, Hospital St. Jaume i Sta Magdalena Mataró (Barcelona), Spain

Received 9 March 1987;


Correspondence to José L. Pérez, Avda. Pompeu Fabra, 12, 5°-D, 08024 Barcelona, Spain

The in-vitro activity of seventeen antibiotics against 177 clinical strains of Streptococcus faecalis was evaluated. Ampicillin and mezlocillin were the most active ß-lactams tested (geometric mean MICs, 0.61 and 0.74 mg/l, respectively). Aminoglycosides showed poor activity and 22.6% of the strains were resistant to 2000 mg/l of streptomycin. No correlation was observed between MICs of gentamicin and streptomycin. Moderate activity was observed when testing norfloxacin and ciprofloxacin. Teicoplanin and co-trimoxazole were extremely active, showing geometric mean MICs of 0.59 and 0.08 mg/l respectively. All strains were susceptible to vancomycin and teicoplanin.


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