Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (15)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Scott, G. R.
Right arrow Articles by Young, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Scott, G. R.
Right arrow Articles by Young, H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (1987) 20, 117-121
© 1987 The British Society for Antimicrobial Chemotherapy

research-article

Ciprofloxacin versus ampicillin and probenecid in the treatment of uncomplicated gonorrhoea in men

G. R. Scotta, A. McMillana and H. Youngb

aDepartment of Genito-Urinary Medicine Royal Infirmary of Edinburgh University of Edinburgh Scotland bBacteriology Department, University of Edinburgh Scotland

accepted 12 January 1987

Eighty-six men with uncomplicated gonorrhoea were entered into a study comparing the efficacy of a single oral dose of 250 mg of ciprofloxacin with a single oral dose of ampicillin 2 g and probenecid 1 g for urethral gonorrhoea and a course of ampicillin, 500 mg four times per day for five days in rectal and pharyngeal infection. Two patients were excluded. Of the remaining 84, 45 were treated with ampicillin and 39 with ciprofloxacin. In the ampicillin group there were two treatment failures out of 40 urethral infections. Three patients with rectal infection were cured. Only one patient out of three pharyngeal infections was cured. Ciprofloxacin cured all of 34 urethral and three rectal infections including one penicillinase producing strain of Neisseria gonorrhoeae (PPNG). Four of five pharyngeal infections were cured but there was one treatment failure. There were no major side effects in either treatment group.

In conclusion, a single oral dose of 250 mg of ciprofloxacin is an effective treatment for uncomplicated gonorrhoea in men.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.