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Journal of Antimicrobial Chemotherapy (1986) 18, 195-198
© 1986 The British Society for Antimicrobial Chemotherapy

research-article

Phamacokinetics of aztreonam in the aqueous humour

G. Harochea, A. Salvanetb, Ch. Lafaixa, Ph. Dubayleb, F. Forestierb, A. Meulmansc and T. Langa

aService de Médecine interne, maladies infectieuses et tropicales. Centre hospitalier intercommunal de Villeneuve St Georges F 94190 bService d'Ophtalmologie, Centre hospitalier intercommunal de Villeneuve St Georges F 94190 cLaboratoire de Pharmacologie, Hôpital Bichat Paris F 75018, France

Received 3 December 1985;

Fifteen patients awaiting cataract extraction were given a 2g intravenous bolus injection of aztreonam. The mean aztreonam concentrations in the aqueous humour, 1, 2 and 4 h after the injection were 1.22, 1.46 and 2.22 mg/l, respectively.


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