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Journal of Antimicrobial Chemotherapy (1986) 17, 453-457
© 1986 The British Society for Antimicrobial Chemotherapy

research-article

In-vitro activity of cefpirome (HR-810), WIN-49375, BMY-28142 and other antibiotics against nosocomially important isolates from cancer patients

Kenneth V. I. Rolston, Maria E. Alvarez, Kou-Ching Hsu and Gerald P. Bodey

University of Texas, M. D. Anderson Hospital and Tumor Institute 6723 Bertner Avenue, Houston, Texas 77030, U.S.A.

accepted 9 September 1985

Reprint requests to: Kenneth V. I. Rolston, M. D. Anderson Hospital Infectious Diseases (47), 6723 Bertner Avenue, Houston, Texas 77030, U.S.A.

The activity of three new antimicrobial agents [cefpirome (HR 810), BMY 28142, WIN 49375], and imipenem was compared to that of four currently available agents, ceftazidime, aztreonam, timentin and piperacillin, against 253 bacterial isolates from cancer patients. The activity of all four agents not yet in clinical use at our institution was significantly greater than that of the four antibiotics already in use.


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