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Journal of Antimicrobial Chemotherapy (1986) 17, 251-253
© 1986 The British Society for Antimicrobial Chemotherapy


research-article

Benzylpenicillin-induced neutropenia

M. S. Al-Hadramy, H. Aman, A. Omer and M. A. Khan

Departments of Medicine and Haematology, King Abdulaziz University Hospital PO Box 6615 Jeddah 21452, Saudi Arabia

accepted 3 October 1985


Neutropenia is a potentially serious complication of parenteral benzylpenicillin administration. It is thought to occur more frequently in patients receiving infusions of stored penicillin solutions. We report three cases of neutropenia produced after bolus injections of freshly prepared benzylpenicillin. Twenty-five other cases were reviewed from the literature and the data summarized.


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