Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Ligtvoet, E. E. J.
Right arrow Articles by Wickerhoff-Minoggio, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ligtvoet, E. E. J.
Right arrow Articles by Wickerhoff-Minoggio, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (1985) 16, 485-490
© 1985 The British Society for Antimicrobial Chemotherapy

research-article

In-vitro activity of pefloxacin compared with six other quinolones

Eric E. J. Ligtvoet* and Thea Wickerhoff-Minoggio

Central Bacteriological laboratory of the Community Hospital Rotterdam The Netherlands

accepted 3 May 1985

The in-vitro antimicrobial activity of pefloxacin was compared with that of three of the newer fluorated quinoline derivates: ciprofloxacin, norfloxacin and enoxacin, as well as with those of the earlier analogues: nalidixic acid, pipemidic acid and cinoxacin, against almost 750 recent patient isolates of medically important bacteria.

MIC90s of pefloxacin were ≤2 mg/l for Enterobacteriaceae, ≤8 mg/l for Pseudomonas aeruginosa, ≤4 mg/l for other nonfermenters and 0·5 mg/l for Staphylococci. Most streptococcal strains were resistant to pefloxacin. Of all the fluorated quinolones, ciprofloxacin was overall the most active compound. The older non-fluorated quinolone analogues had activity against the Enterobacteriaceae only at levels achievable in urine.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Arch OphthalmolHome page
S. X. Stevens, B. D. Fouraker, and H. G. Jensen
Intraocular Safety of Ciprofloxacin
Arch Ophthalmol, December 1, 1991; 109(12): 1737 - 1743.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.