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Journal of Antimicrobial Chemotherapy (1983) 12, 489-496
© 1983 The British Society for Antimicrobial Chemotherapy

research-article

Subjective response to lysine in the therapy of herpes simplex

David E. Walsh*,, Richard S. Griffith{dagger} and Ali Behforooz{ddagger}

*Research Department, General Nutrition Corporation Fargo, North Dakota, U.S.A. {dagger}Department of Medicine, Indiana University School of Medicine Indianapolis, Indiana, U.S.A. {ddagger}Department of Computer Science, University of California at Santa Barbara Santa Barbara, California, U.S.A.

accepted 19 May 1983

Reprint requests to: Dr D. E. Walsh, Research Department, General Nutrition Corporation, P.O. Box 349, Fargo, ND 58107, U.S.A.

To test the effect of lysine supplementation on herpes infection, 1543 subjects were surveyed by questionnaire after a six-month trial period. The study included subjects with cold sores, canker sores, and genital herpes. Of these, 54% had been diagnosed and treated by a physician. The results showed that the average dosage used was 936 mg of lysine daily. Eighty-four per cent of those surveyed said that lysine supplementation prevented recurrence or decreased the frequency of herpes infection. Whereas 79% described their symptoms as severe or intolerable without lysine, only 8% used these terms when taking lysine. Without lysine, 90% indicated that healing took six to 15 days, but with lysine 83% stated that lesions healed in five days or less. Overall, 88% considered supplemental lysine an effective form of treatment for herpes infection.


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[Abstract] [PDF]


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