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Journal of Antimicrobial Chemotherapy (1983) 12, 469-474
© 1983 The British Society for Antimicrobial Chemotherapy


research-article

Susceptibility to mecillinam and other antibiotics and serogroups of enterotoxigenic Escherichia coli from children in Addis Ababa

Gudmund Stintzing and Jette Jacobsen

Department of Pediatrics, Karolinska Institute, St. Göran's Children's Hospital 5-11281 Stockholm, Sweden Bacteriological Research Department, Leo Pharmaceutical Products DK-2750 Ballerup, Denmark

accepted 21 April 1983


The in-vitro susceptibility of 64 strains of enterotoxigenic Escherichia coli (ETEC) was determined for eight antimicrobial agents. The strains were of 27 different O-serogroups of which 078 was the most common. All strains were susceptible to mecillinam, cefoxitin, gentamicin, and trimethoprim-sulphamethoxazole. Two strains were resistant to ampicillin, 15 to doxycycline, 5 to cephalothin, and 13 to chloramphenicol. No difference was found in the antibiotic susceptibility of ETEC strains producing only heat-labile enterotoxin compared with those producing both heat-labile and heat-stable enterotoxin.


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